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BIOL 470-0: Endocrine Disruptors: About EDCs

Major Glands and Examples of Hormones and Function

This is a chart of major glands and examples of hormones and function and their uses. Source: http://www.toxipedia.org

.

Gland

Hormone

Function

Adrenal gland (kidney)

Glucocorticoids

Effects glucose uptake

 

Luteinizing hormone

Female: ovulation - Male: regulates testosterone

 

Adrenaline

Fight-or-flight response (range of effects)

Pituitary gland (brain)

Growth hormone

Growth, cell reproduction

 

Estrogens

Growth, sexual characteristics

Thyroid gland (neck)

Thyroxine (T4)

Metabolism

 

Triiodothyronine (T3)

Metabolism

 

Prolactin

Milk production, sexual gratification

Testes (male)

Testosterone (androgen)

Muscle mass, bone density, sexual maturation

Ovary (female)

Progesterone

Pregnancy, muscle relaxation, range of effects

Pancreas (kidney)

Insulin

Regulates glucose

Pineal gland (brain)

Melatonin

Sleep

 

Thyroid-stimulating hormone

Stimulates thyroid gland to secrete T3 and T4

Endocrine Disruptor Chemicals (EDCs)

This is a chart of Endocrine Distruptor Chemicals (EDCs) and their uses.  For a more complete list of human-made and naturally occuring EDCs, this link opens a 177-page PDF from 2012 that lists chemicals to be tested by the United States Environmental Protection Agency.   Source: http://www.toxipedia.org

Class

Chemical

Use

Pesticide

DDT

Insecticide (no longer allowed in US)

 

2,4-D

Herbicide

 

Atrazine

Herbicide

Plastics additives

Bisphenol A

Harden in plastics

 

Phthalates

Softener in plastics, solvent

Industrial chemical

Nonylphenol (breakdown product of nonylphenol ethoxylates

Detergents, paints, pesticides

Fire retardant

Polybrominated diphenyl ethers (PBDE)

Fire retardant

Drug

Diethylstilbesterol (DES)

No longer used to prevent miscarriages

Contaminants

Dioxin

Byproduct PVC plastics, incineration byproduct, contaminant in certain chlorinated compounds

 

Arsenic, Lead, Mercury

Widespread contaminants

 

Polychlorinated biphenyls (PCB)

Formerly used in transformer oils